Thermo Fisher Scientific TRAcP (Tartrate-Resistant Acid Phosphatase) (Hairy Cell Leukemia Marker) Monoclonal Antibody (SPM601)
TRAcP(Tartrate-Resistant Acid Phosphatase) 단클론 항체(SPM601)는 Hairy Cell Leukemia 마커로 사용되며, 인체·마우스·랫트 시료에 반응합니다. IHC, ICC/IF, Flow Cytometry 등에 적용 가능하며, 단백질 A/G 정제 및 PBS 버퍼에 보존된 액상 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM601 |
| Immunogen | Recombinant full-length human ACP5 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tartrate-resistant acid phosphatase (TRAP) is a basic iron-binding protein with high activity toward phosphoproteins, ATP, and 4-nitrophenyl phosphatase. It is detected in human alveolar macrophages, osteoclasts, spleen, and liver. Its expression is increased in:
- Spleen and monocytes of patients with Gaucher’s disease
- Spleenocytes and circulating leukocytes of patients with hairy cell leukemia
- Spleen of patients with Hodgkin’s lymphoma
- Sera of patients undergoing active bone turnover
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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