
Thermo Fisher Scientific MMP11 Polyclonal Antibody
Rabbit polyclonal antibody against human MMP11 (Stromelysin-3). Validated for WB, IHC, ELISA, and IP at 1:1,000 dilution. Does not cross-react with other MMP family members. Supplied as liquid, 1 mg/mL, stored at 4°C or -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000 |
| ELISA | 1:1,000 |
| Immunoprecipitation (IP) | 1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal domain of human MMP-11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2144716 |
Product Specific Information
- This antibody does not cross-react with other MMP family members.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Stromelysin (MMP-11), a member of the matrix metalloproteinase family, exhibits broad substrate specificity, capable of degrading proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen.
The stromelysin-3 (MMP-11) gene is expressed specifically in stromal cells surrounding invasive breast carcinomas and is localized to the long arm of chromosome 22.
MMP-11 expression is more prominent in malignant tumors compared to benign ones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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