Thermo Fisher Scientific CENP-J Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Chimpanzee

Target Information

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in maintaining centrosome integrity and normal spindle morphology, and is involved in microtubule disassembly at the centrosome.
It can function as a transcriptional coactivator in the Stat5 signaling pathway and as a coactivator of NF-kappaB-mediated transcription, likely via interaction with p300/CREB-binding protein.
Mutations in this gene are associated with primary autosomal recessive microcephaly, characterized by severely reduced brain size and mental retardation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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