
Thermo Fisher Scientific UBR1 Polyclonal Antibody
Thermo Fisher Scientific의 UBR1 Polyclonal Antibody는 Western blot 및 Immunoprecipitation에 적합한 토끼 유래 다클론 항체입니다. Human UBR1 단백질의 1125–1175 아미노산 영역을 면역원으로 제작되었으며, 액상 형태로 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1125 and 1175 of Human Ubiquitin Protein Ligase E3 Component n-Recognin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
ELK1 is a component of the ternary complex that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors.
ELK1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C-terminus, with Ser383 phosphorylation being critical for transcriptional activation.
It acts as a direct target of activated MAP kinase and functions as a nuclear target for the ras-raf-MAPK signaling cascade.
Alternatively spliced transcript variants encoding the same protein have been identified for ELK1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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