Thermo Fisher Scientific IL-13 Polyclonal Antibody
IL-13 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A로 정제된 액상 형태이며, -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from mouse IL-13, amino acids 45–56 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, involved in regulating inflammatory and immune responses. It down-regulates macrophage activity, inhibiting production of pro-inflammatory cytokines and chemokines. IL-13 plays a role in allergen-induced asthma through mechanisms independent of IgE and eosinophils, regulates B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching in B cells. Structurally, IL-13 resembles IL-3, IL-4, IL-5, and GM-CSF. The IL-13 gene is part of a cytokine gene cluster on chromosome 5q, located near IL-4.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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