
Thermo Fisher Scientific FUOM Polyclonal Antibody
Rabbit polyclonal antibody recognizing human FUOM protein. Validated for IHC (paraffin). Detects endogenous FUOM involved in L-fucose interconversion. Supplied as liquid, 1.2 mg/mL, in PBS with 40% glycerol. For research use only.
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Applications
Tested Applications and Dilution
- Immunohistochemistry (Paraffin) (IHC-P): 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length fusion protein of human FUOM (UniProt ID: A2VDF0-1, antigen range: 1–154) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636767 |
Product Specific Information
This antibody detects endogenous levels of total FUOM protein.
Target Information
FUOM is involved in the interconversion between alpha- and beta-L-fucoses.
L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%). The beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases.
Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell–cell adhesion and recognition processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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