Thermo Fisher Scientific OGDH Polyclonal Antibody
Thermo Fisher Scientific OGDH Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 Western blot, IHC, ICC/IF, ELISA에 적합합니다. 미토콘드리아 매트릭스 내 OGDH 단백질을 타깃하며, 고순도 친화 크로마토그래피로 정제된 액상 항체입니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific OGDH Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 148–427 of human OGDH (NP_0010039411) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.67 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805004 |
Product Specific Information
Immunogen sequence:
DPLGILDADL DSSVPADIIS STDKLGFYGL DESDLDKVFH LPTTTFIGGQ ESALPLREII RRLEMAYCQH IGVEFMFIND LEQCQWIRQK FETPGIMQFT NEEKRTLLAR LVRSTRFEEF LQRKWSSEKR FGLEGCEVLI PALKTIIDKS SENGVDYVIM GMPHRGRLNV LANVIRKELE QIFCQFDSKL EAADEGSGDV KYHLGMYHRR INRVTDRNIT LSLVANPSHL EAADPVVMGK TKAEQFYCGD TEGKKVRPRE RRARQIVKAP CSSMEFRSPT
Positive Samples: Mouse kidney, Mouse heart, Mouse brain
Cellular Location: Mitochondrion matrix
Target Information
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex, which catalyzes the conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO₂ during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. Congenital deficiency in 2-oxoglutarate dehydrogenase activity is associated with hypotonia, metabolic acidosis, and hyperlactatemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-88571_OGDH_Q02218-1_Rabbit.svg, PA5-88571_OGDH_Q02218-1_Rabbit_PDP.jpeg)
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