Thermo Fisher Scientific eIF2 gamma Polyclonal Antibody
eIF2 gamma 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ELISA에 적합합니다. Human, Mouse, Rat에 반응하며, Affinity Chromatography로 정제되었습니다. 단백질 합성 개시 복합체 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–250 of human EIF2S3 (NP_0014061) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.02 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855091 |
Product Specific Information
Immunogen sequence:
MAGGEAGVTL GQPHLSRQDL TTLDVTKLTP LSHEVISRQA TINIGTIGHV AHGKSTVVKA ISGVHTVRFK NELERNITIK LGYANAKIYK LDDPSCPRPE CYRSCGSSTP DEFPTDIPGT KGNFKLVRHV SFVDCPGHDI LMATMLNGAA VMDAALLLIA GNESCPQPQT SEHLAAIEIM KLKHILILQN KIDLVKESQA KEQYEQILAF VQGTVAEGAP IIPISAQLKY NIEVVCEYIV KKIPVPPRDF
Target Information
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex is composed of three subunits—eIF2 alpha, eIF2 beta, and eIF2 gamma—that form a ternary complex with GTP and tRNA during early protein synthesis.
eIF2S3 (eukaryotic translation initiation factor 2, subunit 3), also known as eIF2G, is a 472 amino acid protein belonging to the gamma subfamily of GTP-binding elongation factor proteins. It forms a heterotrimer with alpha and beta chains, binds ribosomal subunits, and catalyzes preinitiation complex formation necessary for translation initiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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