Thermo Fisher Scientific ZNF268 Polyclonal Antibody
ZNF268 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. Human과 Mouse 시료에 반응하며, Protein A로 정제된 고순도 항체입니다. -20°C에서 보관하며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ZNF268, amino acids 151–250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, including transcriptional activation or repression. Most zinc-finger proteins possess a krueppel-type DNA binding domain and a KRAB domain, which interacts with KAP1 to recruit histone-modifying proteins.
Zinc finger protein 268 (ZNF268), also known as zinc finger protein 3 or HZF3, is a 947 amino acid protein belonging to the krueppel C2H2-type zinc-finger protein family. It contains 24 C2H2-type zinc fingers and one KRAB domain, localizes to the nucleus, and is involved in transcriptional regulation. ZNF268 is highly expressed in 3–5 week old embryos and has been implicated in human leukemia due to alternatively spliced forms observed in leukemia patients. Two named isoforms exist as a result of alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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