Thermo Fisher Scientific Cenexin-1 Polyclonal Antibody
Thermo Fisher Scientific의 Cenexin-1 Polyclonal Antibody는 인간 및 영장류 시료에서 Cenexin-1 단백질을 검출하기 위한 고품질 항체입니다. Western blot, IHC, ELISA에 사용 가능하며, 친화성 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공합니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:2,000 | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
| ELISA | 1:2,000–1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Chimpanzee, Human, Rhesus monkey |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to residues near the carboxy terminus of Cenexin-1 (ODF2, UniProt ID: Q5BJF6-1). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
This antibody is specific for human Cenexin-1 protein. BLAST analysis suggests cross-reactivity with Cenexin-1 from human, chimpanzee, and macaque based on 100% homology with the immunizing sequence. Cross-reactivity with Cenexin-1 from other sources has not been determined.
Target Information
Cenexin-1 appears to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located outside the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help maintain passive elastic structures and elastic recoil of the sperm tail.
It may modulate sperm motility and functions as a general scaffold protein localized at the distal/subdistal appendages of mother centrioles.
Cenexin-1 is a component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes and is necessary for the formation and/or maintenance of normal CETN1 assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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