Thermo Fisher Scientific YBX1 Polyclonal Antibody
YBX1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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- PA587020
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide of human YBX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2803774 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. It stabilizes cytoplasmic mRNA and modulates translation by interacting with eukaryotic initiation factors. YBX1 also binds promoters containing a Y-box sequence (5'-CTGATTGGCCAA-3'), such as HLA class II genes, regulating transcription. It promotes separation of DNA strands with mismatches or cisplatin modifications, exhibits endonucleolytic activity, and may play a role in DNA repair.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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