Thermo Fisher Scientific PD-L1 (CD274) Polyclonal Antibody, Biotin
PD-L1 (CD274) 단백질을 인식하는 Biotin 결합 폴리클로날 항체로 인간 시료에 반응합니다. Western blot 등 면역학적 분석에 적합하며, 고순도 및 안정적인 액상 형태로 제공됩니다. TBS buffer 기반, -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence CKKQSDTHLEET |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932786 |
Product Specific Information
- This antibody is expected to recognize isoforms a and b (NP_054862.1; NP_001254635.1) only.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Programmed death receptor ligand 1 (PD-L1, also known as B7-H1) is a B7 family member that interacts with programmed death receptor 1 (PD-1). PD-L1 negatively regulates T-cell receptor (TCR) signaling, reducing TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be upregulated upon IFN-gamma stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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