Thermo Fisher Scientific PD-L1 (CD274) Polyclonal Antibody, Biotin

Applications

Western Blot (WB)

• Tested Dilution: 0.3–1 µg/mL
• Publications: [References not provided]

Product Specifications

Product Specific Information

• This antibody is expected to recognize isoforms a and b (NP_054862.1; NP_001254635.1) only.
• Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Target Information

Programmed death receptor ligand 1 (PD-L1, also known as B7-H1) is a B7 family member that interacts with programmed death receptor 1 (PD-1). PD-L1 negatively regulates T-cell receptor (TCR) signaling, reducing TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be upregulated upon IFN-gamma stimulation, suggesting its role in tumor immune evasion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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