
Thermo Fisher Scientific CSF2 Monoclonal Antibody (OTI8F1), TrueMAB
인간 CSF2(GM-CSF)에 특이적인 단클론 항체로 Western blot에 최적화되어 있습니다. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도로 사용 가능합니다. 연구용으로 세포 분화 및 염증 관련 연구에 적합합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F1 |
| Immunogen | Human recombinant protein fragment (aa 18–144 of human CSF2, produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The GM-CSF (CSF2) gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active protein forms a homodimer in the extracellular space.
Located at chromosome region 5q31, this gene cluster includes IL4, IL5, and IL13, and is associated with 5q- syndrome and acute myelogenous leukemia.
Elevated cytokine levels, including GM-CSF, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome.
Knockout mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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