Thermo Fisher Scientific CSF2 Monoclonal Antibody (OTI8F1), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The GM-CSF (CSF2) gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active protein forms a homodimer in the extracellular space.
Located at chromosome region 5q31, this gene cluster includes IL4, IL5, and IL13, and is associated with 5q- syndrome and acute myelogenous leukemia.
Elevated cytokine levels, including GM-CSF, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome.
Knockout mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.

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