Thermo Fisher Scientific Kir7.1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 160-360 of human KCNJ13 (NP_002233.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Kir7.1 (KCNJ13),uniProtId:O60928-1,ncbiNodeId:9606,antigenRange:160-360,antigenLength:360,antigenImageFileName:PA5-109875_Kir7.1_KCNJ13_O60928-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109875_Kir7.1_KCNJ13_O60928-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.56 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855286

Product Specific Information

Immunogen sequence: IARPKNRAFS IRFTDTAVVA HMDGKPNLIF QVANTRPSPL TSVRVSAVLY QERENGKLYQ TSVDFHLDGI SSDECPFFIF PLTYYHSITP SSPLATLLQH ENPSHFELVV FLSAMQEGTG EICQRRTSYL PSEIMLHHCF ASLLTRGSKG EYQIKMENFD KTVPEFPTPL VSKSPNRTDL DIHINGQSID NFQISETGLT E

Target Information

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.