Thermo Fisher Scientific NAPSA Monoclonal Antibody (OTI9F1), TrueMAB
Human NAPSA 단백질(aa 64-244)에 특이적인 Mouse monoclonal antibody. IHC(P) 및 ICC/IF에 1:150 희석으로 사용 가능. Lyophilized 형태, PBS buffer(8% trehalose) 포함. 폐 및 신장 조직 내 Napsin 1 연구용에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 64–244 of human NAPSA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Napsin 1 is an aspartic protease predominantly expressed in the lung, also found in kidney and metastatic carcinomas. It processes surfactant protein B in normal pulmonary and renal tissues but is dysregulated in carcinogenesis.
Napsin evaluation aids in identifying various cancers and distinguishing primary tumors from metastases. Combined with thyroid transcription factor analysis, it serves as a specific biomarker for carcinoma differentiation. Napsin is also associated with pulmonary alveolar proteinosis and protein catabolism in renal tubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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