Thermo Fisher Scientific NGB Monoclonal Antibody (1A11-A9)
인간 NGB 단백질을 인식하는 Mouse monoclonal 항체로 Western blot과 ELISA에 적합합니다. Affinity chromatography로 정제되었으며 PBS(pH 7.4) 용액 형태로 제공됩니다. 뇌 신경세포의 산소 반응 연구 등 신경생물학 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A11-A9 |
| Immunogen | NGB (AAH32509, 1–151 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MERPEPELIR QSWRAVSRSP LGHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E
Target Information
Globins are a superfamily of gas-binding heme proteins found in bacteria, protists, fungi, plants, and animals. They play roles in binding, transport, scavenging, detoxification, and sensing of gases such as oxygen, nitric oxide, and carbon monoxide.
Neuroglobin (Ngb) is a hexacoordinate hemoglobin predominantly expressed in the vertebrate brain, enhancing oxygen supply to neural tissues. Its high affinity for oxygen and expression in cerebral neurons suggest a role in responses to hypoxia or ischemia. In vitro neuronal hypoxia elevates neuroglobin levels, improving neuronal survival. The human neuroglobin gene maps to chromosome 14q24 and encodes a 151 amino acid protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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