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Thermo Fisher Scientific PPP4R3 Alpha Polyclonal Antibody
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Thermo Fisher Scientific PPP4R3 Alpha Polyclonal Antibody

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PPP4R3 Alpha 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 사용 가능. Human PPP4R3A의 C-말단 영역을 면역원으로 제작. 액상 형태, 4°C 보관, 1년 권장 보관 기간. 연구용으로만 사용.

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pk
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Thermo Fisher Scientific · Thermo Fisher Scientific PPP4R3 Alpha Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1:2,000–1:10,000
Immunohistochemistry (IHC) 1:50–1:500
Immunohistochemistry (Paraffin) (IHC (P)) 1:100–1:500
Immunoprecipitation (IP) 2–5 µg/mg lysate

Product Specifications

Specification Description
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Region between residue 770 and the C-terminus (residue 820) of Human Protein Phosphatase 4, Regulatory Subunit 3 Alpha (KIAA2010)
Conjugate Unconjugated
Form Liquid
Concentration 0.20 mg/mL
Storage Conditions 4°C
Shipping Conditions Wet ice

Product Specific Information

  • Recommended shelf life: 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

Target Information

Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers.
The PPP4C–PPP4R2–PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX), generated during DNA replication and required for DNA double-strand break repair.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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