
Thermo Fisher Scientific ATP11B Polyclonal Antibody
인간 ATP11B 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:200~1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액에 보관. 세포 생존 및 인산지질 수송 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ATP11B. Recombinant protein control fragment (Product #RP-96268). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638349 |
Product Specific Information
Immunogen sequence:
MKYQEINGRL VPEGPTPDSS EGNLSYLSSL SHLNNLSHLT TSSSFRTSPE NETELIKEHD LFFKAVSLCH TVQISNVQTD CTGDGPWQSN LAPSQLEY
Sequence identity:
- Mouse: 79%
- Rat: 80%
Target Information
ATP11B is a widely expressed integral membrane ATPase thought to drive phospholipid transport across membranes. It may be hormonally regulated and involved in subnuclear trafficking of transcription factors with RING motifs. Although the exact transported molecule is unknown, increased expression of homologous ATP11A has been linked to resistance to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting ATP11B may contribute to cell survival under stress conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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