Thermo Fisher Scientific CEP41 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human CEP41(Accession Q9BYV8), corresponding to amino acid residues D182-A232. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CEP41,uniProtId:Q9BYV8-1,ncbiNodeId:9606,antigenRange:182-232,antigenLength:373,antigenImageFileName:PA5-103727_CEP41_Q9BYV8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103727_CEP41_Q9BYV8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2853060

Product Specific Information

Antibody detects endogenous levels of total CEP41.

Target Information

Centrosomes are the major microtubule-organizing centers of mammalian cells. They are composed of a centriole pair and surrounding microtubule-nucleating material termed pericentriolar material (PCM). Bipolar mitotic spindle assembly relies on two intertwined processes: centriole duplication and centrosome maturation. Failure to properly orchestrate centrosome duplication and maturation is subsequently linked to spindle defects, which can result in aneuploidy and promote cancer progression. The CEP41 (centrosomal protein of 41 kDa) gene encodes a protein of 373 amino acids that is alternatively spliced into 4 isoforms. Isoforms 1 and 4 are expressed in testis, as well as in and fetal brain and liver.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.