Thermo Fisher Scientific FCRL2/FCRL5 Monoclonal Antibody (296902)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Flow Cytometry (Flow)

2.5 µg per million cells

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

296902

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FCRL2/FcRH2 Glu15-Asp395 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FCRL2/FCRL5,uniProtId:Q96LA5-1,ncbiNodeId:9606,antigenRange:15-395,antigenLength:508,antigenImageFileName:MA5-24005_FCRL2FCRL5_Q96LA5-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24005_FCRL2FCRL5_Q96LA5-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2606017

Product Specific Information

Detects human FCRL2/FcRH2 and FCRL5/FcRH5 in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant human FCRL1, FCRL3, and FCRL4 is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

Fc receptor homologs, also known as IRTA2 proteins, are transmembrane proteins with sequence homology to classical Fc receptor families. FcRH2 (FCRL2) may have a regulatory role in normal and neoplastic B cell development. FcRH5 (FCRL5) expression is deregulated in multiple myeloma and Burkitt lymphoma cell lines with 1q21 abnormalities. FCRL5 may be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. It also may have an immunoregulatory role in marginal zone B-cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.