Thermo Fisher Scientific TMEM123 Monoclonal Antibody (297617)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Flow Cytometry (Flow)

2.5 µg per million cells

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

297617

Immunogen

CHO-derived recombinant human Porimin His27-Ser149 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TMEM123,uniProtId:Q8N131-1,ncbiNodeId:9606,antigenRange:27-149,antigenLength:208,antigenImageFileName:MA5-24007_TMEM123_Q8N131-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24007_TMEM123_Q8N131-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2606735

Product Specific Information

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

Transmembrane protein 123, or Tmem123, is a single-pass type I membrane protein and belongs to the CD164 family. Tmem123 acts as a novel marker for DC maturation. DCs are also known as professional antigen-presenting cells. It is reported that the Tmem123 molecule may be closely associated with the cell surface expression of CD40. It was also reported previously that Tmem123 protein may also be responsible for oncotic cell death, which is characterized by cell swelling, organelle swelling, vacuolization, increased membrane permeability and cell adhesion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.