Thermo Fisher Scientific DEC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2-4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

5 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide (34 YQVYKSRRGIKRSEDSKE 51) of Dec1 protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.0 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2541002

Target Information

Dec1, which is also known as Stra13 or Sharp2, is a basic helix-loop-helix (bHLH) transcription factorthat has beenfound to play an important role in circadian system. Dec1contains one basic helix-loop-helix (bHLH) domain, one Orange domain and is reported to be expressed in Treg cells. It is also reported that Dec1 is required for long-term maintenance of Treg cells after adoptive transfer to suppress effector T cell-mediated inflammation. Dec1 positively regulates CD25 expression in association with Runx 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.