Thermo Fisher Scientific WEE1 Monoclonal Antibody (5B6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

5B6

Immunogen

WEE1 (NP_003381, 289 a.a. approximately 388 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:WEE1,uniProtId:P30291-1,ncbiNodeId:9606,antigenRange:289-388,antigenLength:646,antigenImageFileName:H00007465-M01A_WEE1_P30291-1_House_mouse.svg,antigenImageFileNamePDP:H00007465-M01A_WEE1_P30291-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: SNMKSRYTTE FHELEKIGSG EFGSVFKCVK RLDGCIYAIK RSKKPLAGSV DEQNALREVY AHAVLGQHSH VVRYFSAWAE DDHMLIQNEY CNGGSLADAI

Target Information

WEE1, which is classified as a Ser/Thr kinase by sequence analysis, has been shown to inactivate multiple CDKs by tyrosine phosphorylation. Wee1 protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.