Thermo Fisher Scientific ACSL6 Polyclonal Antibody
ACSL6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, 인간·마우스·랫트 반응성. 액상 형태, 1 mg/mL 농도, -20°C 보관. 지방산 대사 연구용으로 최적화된 항체.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ACSL6 (Accession Q9UKU0), corresponding to amino acid residues N498–G548 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851086 |
Product Specific Information
Antibody detects endogenous levels of total ACSL6.
Target Information
FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in the brain, and the acyl-CoAs produced may be utilized exclusively for the synthesis of brain lipids.
FACL6 is expressed predominantly in erythrocyte precursors, especially in reticulocytes, fetal blood cells derived from fetal liver, hematopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes.
This protein is associated with myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5;12)(q31;p13) involving ETV6 and ACSL6.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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