Thermo Fisher Scientific Phospho-MAPK15 (Thr175, Tyr177) Polyclonal Antibody
MAPK15의 Thr175 및 Tyr177 인산화 부위를 인식하는 rabbit polyclonal antibody로, WB 및 ICC/IF에 적합합니다. 액상 형태이며 1 mg/mL 농도, -20°C 보관. 세포 성장 및 분화 연구용으로 사용됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-MAPK15 (Thr175, Tyr177) Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ERK8 around the phosphorylation site of Thr175 and Tyr177 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2902995 |
Target Information
The ERKs are a subfamily of MAPKs implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase regulated by serum and the c-Src non-receptor tyrosine kinase.
ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in nuclear receptor regulation beyond estrogen receptor alpha.
Erk8 is also a novel effector of RET/PTC3 and therefore involved in RET biological functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.