Thermo Fisher Scientific GluR4 Polyclonal Antibody
GluR4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), IP 등에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공. 신경세포 내 흥분성 신호전달 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Immunoprecipitation (IP) | 2–5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of Glutamate R4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Brain tissue
- Cellular location: Cytoplasmic, membrane
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development, and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. These receptors are primarily responsible for fast excitatory neurotransmission by glutamate, whereas NMDA receptors are characterized by slower kinetics and high permeability for Ca²⁺ ions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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