Thermo Fisher Scientific S1P3, Sphingosine 1-Phosphate Receptor 3 Polyclonal Antibody
S1P3(Sphingosine 1-Phosphate Receptor 3) 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 검증 완료. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. 액상 형태, 1 mg/mL 농도, 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide representing the carboxyl-terminal tail of human S1P3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping conditions | Wet ice (domestic); Dry ice (international) |
Target Information
EDG-3 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-3 is sphingosine-1-phosphate. There are eight known members of the EDG receptor family, implicated in mediating growth-related effects such as induction of cellular proliferation, differentiation, survival, and suppression of apoptosis. They also evoke cellular effector functions dependent on cytoskeletal responses such as contraction, secretion, adhesion, and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG-3 is expressed in cardiovascular, leukocyte-containing, and other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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