Thermo Fisher Scientific Human MATN4 Synthetic Peptide

Thermo Fisher Scientific Human MATN4 Synthetic Peptide

Applications

• Control (Ctrl): Assay-dependent
• Blocking Assay (BLOCK): Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 13 amino acids near the amino terminus of human MATN4.
PEP-0849 can be used as a blocking peptide with polyclonal antibody PA5-20735.

Target Information

Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks.
Members of the matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains, and a coiled coil alpha-helical module.
MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices such as embryonic kidney, lung, bone, cartilage, and nervous system.
The matrilin genes are strictly and differently regulated, and their expression may serve as markers for cellular differentiation.
MATN4 could serve as an odontoblast differentiation marker, e.g., in odontoblast stem cell research.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.