Thermo Fisher Scientific FZD8 Polyclonal Antibody
Rabbit polyclonal antibody targeting human FZD8 protein. Validated for ICC/IF applications at 0.25–2 µg/mL. Purified by antigen affinity chromatography and supplied in PBS with glycerol and sodium azide. Suitable for cancer and tissue expression research.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FZD8 (control fragment: Product #RP-107796) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2857079 |
Product Specific Information
Immunogen sequence:QCRAPMVSVS SERHPLYNRV KTGQIANCA
Target Information
Members of the Frizzled family encode seven-transmembrane domain proteins that act as receptors for Wingless-type MMTV integration site family signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway.
Frizzled 8 (FZD8) is highly expressed in certain human cancer cell lines, suggesting a role in cancer development. It is expressed in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis, as well as various tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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