Thermo Fisher Scientific ARTS Polyclonal Antibody
Human ARTS 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 1 mg/mL 농도. 인간 폐 조직 lysate를 양성 대조로 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (IHC) | 2 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids near the amino terminus of human ARTS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153248 |
Product Specific Information
- In Western blot applications, this antibody detects a band at approximately 32 kDa.
- A suggested positive control is human lung tissue lysate.
- PA5-20001 can be used with blocking peptide PEP-0123.
Target Information
Apoptosis is related to many diseases and developmental processes. Mitochondrial proteins such as cytochrome c, Apaf-1, and AIF play important roles in apoptosis. A novel mitochondrial septin-like protein, designated ARTS (Apoptosis Related Protein in TGF-beta Signaling Pathway), was identified recently.
ARTS, encoded by the human septin H5/PNUTL2/CDCrel2b gene, localizes to mitochondria and translocates to the nucleus during apoptosis. It is expressed in many tissues and enhances cell death induced by TGF-beta, and to a lesser extent, by other apoptotic agents such as TNF-α and Fas ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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