Thermo Fisher Scientific Cytokeratin 3 Polyclonal Antibody
Thermo Fisher Scientific의 Cytokeratin 3 Polyclonal Antibody는 인간 시료 반응성을 가지며 WB, ICC/IF, ELISA에 사용 가능. Rabbit IgG 기반의 비결합형 액상 항체로, 고순도 친화 크로마토그래피 정제. 각막 상피 연구 및 단백질 발현 분석에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 230–390 of human KRT3 (NP_4764292) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.73 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804316 |
Product Specific Information
- Immunogen sequence:
WNLLQQQGTS SISGTNNLEP LFENHINYLR SYLDNILGER GRLDSELKNM EDLVEDFKKK YEDEINKRTA AENEFVTLKK DVDSAYMNKV ELQAKVDALI DEIDFLRTLY DAELSQMQSH ISDTSVVLSM DNNRSLDLDS IIAEVRAQYE DIAQRSKAEA E - Positive Samples: H460
Target Information
Cytokeratin 3 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12, and mutations in these genes have been associated with Meesmann’s Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12–q13. (NCBI Gene description)
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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