Thermo Fisher Scientific DAP3 Monoclonal Antibody (OTI1A12), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are involved in mitochondrial protein synthesis.
Mitochondrial ribosomes (mitoribosomes) consist of a 28S small subunit and a 39S large subunit, with a higher protein-to-rRNA ratio (approximately 75%) compared to prokaryotic ribosomes.
Unlike prokaryotic ribosomes, mammalian mitoribosomes lack 5S rRNA.
The DAP3 gene encodes a 28S subunit protein that also participates in apoptotic pathways initiated by TNF-α, Fas ligand, and IFN-γ.
This protein may bind ATP/GTP and interact with mitoribosomal protein S27.
Splice variants differing in the 5′ UTR exist but encode the same protein.
Pseudogenes have been identified on chromosomes 1q and 2q.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.