Thermo Fisher Scientific MRPL39 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 39-338 of human MRPL39 (NP_059142.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MRPL39,uniProtId:Q9NYK5-1,ncbiNodeId:9606,antigenRange:39-338,antigenLength:338,antigenImageFileName:PA5-120065_MRPL39_Q9NYK5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120065_MRPL39_Q9NYK5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.01 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913637

Product Specific Information

Positive test controls include: DU145, K-562, A-431, 293T, Mouse liver, Mouse heart, Mouse kidney, Rat liver. The target is usually found in the following locations: Mitochondrion.

Immunogen sequence: ELTEMRNDLF NKEKARQLSL TPRTEKIEVK HVGKTDPGTV FVMNKNISTP YSCAMHLSEW YCRKSILALV DGQPWDMYKP LTKSCEIKFL TFKDCDPGEV NKAYWRSCAM MMGCVIERAF KDEYMVNLVR APEVPVISGA FCYDVVLDSK LDEWMPTKEN LRSFTKDAHA LIYKDLPFET LEVEAKVALE IFQHSKYKVD FIEEKASQNP ERIVKLHRIG DFIDVSEGPL IPRTSICFQY EVSAVHNLQP TQPSLIRRFQ GVSLPVHLRA HFTIWDKLLE RSRKMVTEDQ SKATEECTST

Target Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.