Thermo Fisher Scientific PTPN23 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MGPQAAPLTI RGPSSAGQST PSPHLVPSPA PSPGPGPVPP RPPAAEPPPC LRRGAAAADL LSSSPESQHG GTQSPGGGQP LLQPTKVDAA EGRRPQALRL IERDPYEHPE RLRQLQQELE AFRGQLGDVG ALDTVWRELQ DAQEHDARGR SIAIARCYSL KNRHQDVMPY DSNRVVLRSG KDDYINASCV EGLSPYCPPL VATQAPLPGT AADFWLMVHE QKVSVIVMLV SEAEMEKQKV ARYFPTERGQ PMVHGALSLA LSSVRSTETH VERVLSLQFR DQSLKRSLVH LHFPTWPELG LPDSPSNLLR FIQEVHAHYL HQRPLHTPII VHCSSGVGRT GAFALLYAAV QEVEAGNGIP ELPQLVRRMR QQRKHMLQEK LHLRFCYEAV VRHVEQVLQR HGVPPPCKPL ASASISQKNH LPQDSQDLVL GGDVPISSIQ ATIAKLSIRP PGGLESPVAS LPGPAEPPGL PPASLPESTP IPSSSPPPLS SPLPEAPQPK EEPPVPEAPS SGPPSSSLEL LASLTPEAFS LDSSLRGKQR MSKHNFLQAH NGQGLRATRP SDDPLSLLDP LWTLNKT

Target Information

Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.