Thermo Fisher Scientific LETMD1 Polyclonal Antibody, MaxPab
Thermo Fisher LETMD1 폴리클로날 항체는 인간 LETMD1 단백질을 표적으로 하며, Western blot 실험에 적합합니다. HCCR-1 관련 종양 연구 및 p53 조절 기전 탐구에 활용 가능하며, 고순도 친화 크로마토그래피로 정제된 액상 형태입니다.
- 카탈로그번호
- H00025875-B01P
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific LETMD1 Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | LETMD1 (NP_056231.3, 1–360 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MALSRVCWAR SAVWGSAVTP GHFVTRRLQL GRSGLAWGAP RSSKLHLSPK ADVKNLMSYV VTKTKAINGK YHRFLGRHFP RFYVLYTIFM KGLQMLWADA KKARRIKTNM WKHNIKFHQL PYREMEHLRQ FRQDVTKCLF LGIISIPPFA NYLVFLLMYL FPRQLLIRHF WTPKQQTDFL DIYHAFRKQS HPEIISYLEK VIPLISDAGL RWRLTDLCTK IQRGTHPAIH DILALRECFS NHPLGMNQLQ ALHVKALSRA MLLTSYLPPP LLRHRLKTHT TVIHQLDKAL AKLGIGQLTA QEVKSACYLR GLNSTHIGED RCRTWLGEWL QISCSLKEAE LSLLLHNVVL LSTNYLGTRR
Target Information
HCCR-1 (human cervical cancer oncogene 1), also known as HCCR-2 or LETMD1, is a 360 amino acid single-pass membrane protein expressed in kidney, liver, skeletal muscle, heart, and brain.
It may be involved in tumorigenesis and function as a negative regulator of the p53 tumor suppressor.
Overexpression of HCCR-1 can cause mitochondrial dysfunction leading to apoptosis resistance and tumor progression.
HCCR-1 is considered a candidate biomarker for breast cancer and is highly expressed in various human tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon, and uterine cervix.
Six isoforms exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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