Thermo Fisher Scientific RAD17 Polyclonal Antibody
Thermo Fisher Scientific RAD17 Polyclonal Antibody는 인간 RAD17 단백질을 검출하는 토끼 유래 IgG 항체로, Western blot에 최적화되어 있습니다. 1 mg/mL 농도의 액상 형태이며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 성장과 DNA 손상 체크포인트 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
- Publications: [참조 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues N(2) Q V T D W V D P S F D D F(15) of human RAD17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560815 |
Product Specific Information
PA1-4132 detects human RAD17.
It has been successfully used in Western blot procedures.
By Western blot, this antibody detects a ~66 kDa protein representing RAD17 in human heart lysate.
The PA1-4132 immunogen is a synthetic peptide corresponding to residues N(2) Q V T D W V D P S F D D F(15) of human RAD17.
Target Information
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage.
It has a weak ATPase activity required for binding to chromatin.
Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation.
May serve as a sensor of DNA replication progression and may be involved in homologous recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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