Thermo Fisher Scientific RAD17 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues N(2) Q V T D W V D P S F D D F(15) of human RAD17. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RAD17,uniProtId:O75943-1,ncbiNodeId:9606,antigenRange:2-15,antigenLength:681,antigenImageFileName:PA1-4132_RAD17_O75943-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4132_RAD17_O75943-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_560815

Product Specific Information

PA1-4132 detects human RAD17.

PA1-4132 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~66 kDa protein representing RAD17 in human heart lysate.

The PA1-4132 immunogen is a synthetic peptide corresponding to residues N(2) Q V T D W V D P S F D D F(15) of human RAD17.

Target Information

Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.