Thermo Fisher Scientific Plasminogen Polyclonal Antibody, Biotin
인간 유래 플라스미노겐을 인식하는 염소 다클론 항체로, 비오틴 결합 형태입니다. Western blot과 ELISA에 적합하며, 높은 민감도와 특이성을 제공합니다. 4°C 단기 보관, 장기 보관 시 -20°C에서 냉동 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
ELISA
- Tested Dilution: 1:20,000–1:100,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Plasminogen from human plasma |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 10 mg/mL |
| Purification | IgG fraction |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl, 10 mg/mL BSA |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_795198 |
Product Specific Information
PA1-26883 detects Plasminogen from human samples.
Target Information
Plasminogen is a plasma protein synthesized mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of approximately 88.5 kDa. The plasma concentration is usually in the range of 70–200 mg/L.
It is activated by tissue-plasminogen activator, urokinase, and streptokinase to form plasmin. Activation results from cleavage and release of the preactivation peptide.
Plasmin consists of a heavy (A-) chain containing five kringles and a light (B-) chain with the active site. It is a trypsin-like protease whose natural substrate is fibrin, and binding sites for fibrin reside on the kringles.
Plasmin is essential for fibrinolysis; decreased fibrinolytic potential due to congenital defects in plasmin can lead to recurring thrombosis, thrombophlebitis, and pulmonary embolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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