Thermo Fisher Scientific RB1 Monoclonal Antibody (OTI1C3), TrueMAB
RB1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 1:2,000 희석으로 사용 가능. Human RB1(aa 309-590) 재조합 단백질로 면역화됨. 액상 형태로 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 309–590 of human RB1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine residues but not on tyrosine. It forms complexes with SV40 large T antigen, adenovirus E1A, and human papillomavirus-16 E. Rb protein may act by regulating transcription, and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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