Thermo Fisher Scientific USP11 Polyclonal Antibody
USP11 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 Immunoprecipitation에 적합합니다. 인간 USP11의 870–920번째 잔기 구간을 면역원으로 제작되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 870 and 920 of Human ubiquitin specific peptidase 11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the ubiquitin pathway. Localized to the nucleus, USP11 associates with both Ran BP-M (Ran binding protein M) and the tumor suppressor BRCA2. Through these associations, USP11 functions to either inhibit ubiquitination of these proteins or remove ubiquitin residues already attached. USP11 is implicated in several X-linked retinal diseases and may play a role in tumor suppression due to its ability to deubiquitinate BRCA2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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