Thermo Fisher Scientific SGSM1 Polyclonal Antibody
인간 SGSM1 단백질에 특이적인 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼와 40% 글리세롤로 안정화되어 있습니다. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA552038
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SGSM1. Recombinant protein control fragment (Product # RP-91520) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647220 |
Product Specific Information
Immunogen sequence:
SPDSGHPSSH NFSSGLSEHS EPSLSTEDSV LDAQRNTPTV LRPRDGSVDD RQSSEATTSQ DEAPREELAV QDSLESDLLA NESMDEFMSI TGSLDMALPE KDDVVMEGWR SSETEKHGQA DSEDNLSEEP EMESLFPALA SLAVTT
- Highest antigen sequence identity to orthologs:
- Mouse: 83%
- Rat: 83%
Target Information
Small G proteins such as RAP and RAB are key molecules in intracellular signal transduction and vesicle transport.
The small G protein signaling modulator (SGSM) family, including SGSM1–3, binds to RAP and RAB family proteins.
All SGSM proteins contain both RUN and TBC domains.
SGSM1 (RUTBC2) is a 1,148 amino acid protein localized to the Golgi apparatus and mainly expressed in the CNS.
It interacts with RAP and RAB subfamily members, functioning as a modulator of RAP- and RAB-mediated neuronal signal transduction and vesicular transport pathways.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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