Thermo Fisher Scientific Phospho-HSP27 (Ser78) Polyclonal Antibody
Phospho-HSP27 (Ser78) 인산화 단백질을 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, Human, Dog, Horse, Non-human primate 시료에서 반응. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공.
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Applications
Western Blot (WB)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Horse, Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (73 YSRAL(S)RQLSS 83) of Phospho-HSP27 pSer78 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540864 |
Target Information
In response to adverse environmental changes, cells from many organisms increase expression of heat shock or stress proteins.
HSPB1 (heat shock protein beta-1 or HSP27) is a small heat shock protein functioning as a molecular chaperone to maintain denatured proteins in a folding-competent state.
It plays a role in stress resistance and actin organization. Through its molecular chaperone activity, HSP27 regulates numerous biological processes including phosphorylation and axonal transport of neurofilament proteins.
Mutations in the gene can result in Charcot-Marie-Tooth disease 2F and Neuronopathy distal hereditary motor 2B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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