Thermo Fisher Scientific CD100 (Semaphorin-4D) Monoclonal Antibody (SEMA4D/933)
CD100(Semaphorin-4D)을 인식하는 Thermo Fisher Scientific의 단클론 항체로, 인간 및 영장류 시료에 반응합니다. ICC/IF 및 유세포분석에 적합하며, Protein A/G로 정제된 액상 항체입니다. PBS(pH 7.4) 버퍼에 보존되며 방부제는 포함하지 않습니다.
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Applications and Tested Dilution
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–2 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SEMA4D/933 |
| Immunogen | Human recombinant SEMA4D protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Semaphorins are neuronal chemorepellents that direct pioneering neurons during nervous system development.
CD100 (also known as Semaphorin 4D), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and enhances their viability in vitro.
CD100 modifies CD40–CD40L B cell signaling by promoting B cell aggregation and survival while downregulating CD23 expression.
CD72 serves as a lymphocyte receptor for the class IV semaphorin CD100, regulating B cell signaling.
CD100 is expressed on resting and PHA-stimulated T cells, weakly expressed on NK cells, EBV-transformed B cells, monocytes, and tumor/peripheral blood T cell lines, and at higher levels on activated T and B cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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