Thermo Fisher Scientific SERPINB4 Recombinant Rabbit Monoclonal Antibody (001)
Human SerpinB4/SCCA2 단백질을 인식하는 재조합 토끼 단클론 항체. IHC(P)에서 1:100~1:500 희석으로 사용 가능. 동물 유래 성분이 없는 포뮬레이션으로 로트 간 일관성 보장. 단기 4°C, 장기 -20°C 보관.
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- MA529558
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 001 |
| Immunogen | Recombinant Human SerpinB4/SCCA2 protein (Met1–Pro390) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785404 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal clones.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the large rabbit immune repertoire
This antibody has specificity for Human SerpinB4/SCCA2.
Target Information
SERPINB4, also known as squamous cell carcinoma antigen 2 (SCCA-2) or leupin, directly inhibits human granzyme proteolytic activity. Overexpression of SERPINB4 in HeLa cells inhibits recombinant granzyme-induced as well as NK cell-mediated cell death.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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