ELK Biotechnology CKAP2 rabbit pAb
CKAP2 단백질을 인식하는 토끼 폴리클로날 항체로, 세포골격 및 세포분열 연구에 적합합니다. WB에서 사용 가능하며, 사람과 생쥐 시료에 반응합니다. 합성 펩타이드 면역원으로 제작되었으며, -20°C에서 1년 보관 가능합니다.
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ELK Biotechnology CKAP2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CKAP2 rabbit pAb |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human CKAP2 (AA range: 298–348) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 26586 |
| Human Swiss-Prot No. | Q8WWK9 |
| Species Reactivity | Human, Mouse |
Cellular Localization
Cytoplasm, cytoskeleton, spindle, spindle pole.
Endogenous CKAP2 does not colocalize with microtubules in G1, S, and early G2.
At late G2 and prophase, after separation of duplicated centrosomes, it colocalizes with gamma-tubulin and centrosome-proximal microtubules.
From prometaphase through anaphase B, it colocalizes with mitotic spindle poles and spindle microtubules.
During cytokinesis, it is absent from midbody microtubules.
Background
This gene encodes a cytoskeleton-associated protein that stabilizes microtubules and plays a role in regulating cell division.
The encoded protein is regulated through phosphorylation at multiple serine and threonine residues.
A pseudogene of this gene exists on chromosome 14.
Alternative splicing results in multiple transcript variants.
[provided by RefSeq, Nov 2013]
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