Thermo Fisher Scientific TFR2 Polyclonal Antibody
TFR2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. Human 시료에 반응하며, 합성 펩타이드로 면역생성. PBS 및 2% sucrose 용액에 보관되며, -20°C에서 보존 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | 5 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human TFR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576506 |
Product Specific Information
Peptide sequence:
YVSLDNAVLG DDKFHAKTSP LLTSLIESVL KQVDSPNHSG QTLYEQVVFT
Sequence homology:
Cow: 93%
Dog: 93%
Guinea Pig: 86%
Human: 100%
Mouse: 100%
Pig: 93%
Rabbit: 100%
Rat: 100%
Target Information
This gene belongs to the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease-associated (PA) domain, an M28 peptidase domain, and a transferrin receptor-like dimerization domain.
The protein mediates cellular uptake of transferrin-bound iron, and mutations in this gene are associated with hereditary hemochromatosis type III.
Alternatively spliced variants encoding different isoforms have been described, though not all variants are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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