Thermo Fisher Scientific Tapasin Polyclonal Antibody
Human Tapasin 단백질(C-terminal, aa 307-356)에 특이적인 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 검증 완료. 0.5 mg/mL 농도, PBS + 2% sucrose buffer, -20°C 보관. 항원 처리 및 MHC class I 복합체 연구용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:600 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human TAPBP (aa 307–356) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610334 |
Product Specific Information
- Peptide sequence: GEAPPELLCL VSHFYPSGGL EVEWELRGGP GGRSQKAEGQ RWLSALRHHS
- Sequence homology: Cow: 86%; Human: 100%; Pig: 86%; Sheep: 86%
Target Information
This gene encodes a transmembrane glycoprotein that mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP). This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may bind to a single TAP molecule. The protein contains a C-terminal double-lysine motif (KKKAE) that maintains membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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