Thermo Fisher Scientific PSG1 Polyclonal Antibody
인간 PSG1 단백질을 인식하는 Rabbit Polyclonal Antibody로 다양한 면역실험(WB, IHC, ICC, ELISA)에 적합. 고순도 Affinity Chromatography 정제 및 안정적인 PBS/glycerol 저장용액 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific PSG1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 180–419 of human PSG1 (NP_001171754.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.03 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855641 |
Product Specific Information
Immunogen sequence:
WWMNGQSLPM THSLKLSETN RTLFLLGVTK YTAGPYECEI RNPVSASRSD PVTLNLLPKL PKPYITINNL NPRENKDVLN FTCEPKSENY TYIWWLNGQS LPVSPRVKRP IENRILILPS VTRNETGPYQ CEIRDRYGGI RSDPVTLNVL YGPDLPRIYP SFTYYRSGEV LYLSCSADSN PPAQYSWTIN EKFQLPGQKL FIRHITTKHS GLYVCSVRNS ATGKESSKSM TVEVSDWTVP
Target Information
Human pregnancy-specific glycoproteins (PSG) are a group of closely related secreted glycoproteins highly expressed in placental syncytiotrophoblast cells of fetal origin. PSG are commonly expressed in tumors of trophoblast origin such as hydatidiform mole and choriocarcinoma. They represent the most abundant fetal protein in maternal blood at term.
The eleven human PSG genes (PSG1–PSG11) form, together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes, the CEACAM gene family. PSG stimulates secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17. PSG are thought to modulate the maternal immune system during pregnancy, protecting the semiallotypic fetus from rejection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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