Thermo Fisher Scientific TGIF1 Monoclonal Antibody (OTI2E7), TrueMAB
인간 TGIF1 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로 Western Blot에 최적화되어 있습니다. 비결합형 액상 형태이며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며 안정적인 장기 보관이 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E7 |
| Immunogen | Full length human recombinant protein of human TGIF1 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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