Thermo Fisher Scientific ATOH1 Polyclonal Antibody
Rabbit polyclonal antibody against ATOH1 (MATH1) for WB, IHC, and SPR applications. Reacts with human and mouse. Affinity purified, unconjugated, supplied in PBS with sucrose and sodium azide. For research use only.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 0.2–1.0 µg/mL | |
| Immunohistochemistry (IHC) | Assay-dependent | |
| Surface Plasmon Resonance (SPR) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human MATH1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688626 |
Product Specific Information
This target displays homology in the following species:
Cow: 92%; Dog: 85%; Horse: 85%; Human: 100%; Mouse: 92%; Pig: 92%; Rabbit: 83%; Rat: 77%
Target Information
The Drosophila atonal gene produces a protein with basic helix-loop-helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 1 (MATH-1), also known as Atoh1, Ath1, or HATH-1, is a 351 amino acid protein with an atonal-related basic HLH domain. In mice, expression of MATH-1 occurs by embryonic day 9.5 and initially localizes to the cranial ganglions and the dorsal part of the central nervous system. Expression becomes restricted to the external granular layer of the cerebellum by day 18 and is undetectable in adult nervous tissue. MATH-1 may play a role in differentiation of subsets of neural cells via activation of E box-dependent transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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