Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI11C3), TrueMAB
인간 KLK8 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot과 IHC(P) 실험에 적합. 고순도 친화성 크로마토그래피 정제, 1 mg/mL 농도. 연구용으로만 사용 가능하며 암 및 질병 바이오마커 연구에 활용 가능.
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Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI11C3), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11C3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–260 of human KLK8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological functions. Many kallikreins are implicated in carcinogenesis and may serve as novel cancer and disease biomarkers.
KLK8 is one of fifteen kallikrein subfamily members located in tandem on chromosome 19. The encoded protein may be involved in proteolytic cascades in the skin and serve as a biomarker for ovarian cancer. Alternate splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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